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Skin Barrier Support L-Histidine Supplement

$66

Age: 4-12 years

A daily kids (4-12 years) berry gummy dietary supplement with key vitamins, minerals, and L-histidine to help fortify the skin barrier (by building skin barrier protein filaggrin and natural moisturization factor), reduce water loss, smooth roughness, and protect against allergens and pollution. A healthy skin barrier means less skin sensitivity and de-hydration.

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Clinical Results

49%

decrease in average SCORAD in 12 weeks*

95%

decrease in average SCORAD in 8 weeks in 100% of subjects when paired with Bia Eczema Relief Lotion and Bia Unscented Soap**

97%

decrease in NRS (itch) in 100% of subjects when paired with Bia Eczema Relief Lotion and Bia Unscented Soap**

*Double-blind study, 25 children, aged 1 to 7 with mild to moderate atopic dermatitis over 12 weeks (Intertek, UK, 2020). Publication: http://dx.doi.org/10.2147/CCID.S146760
** Eurofins Open-label Study, 40 children ages 4 to 12 with mild to moderate atopic dermatitis over 8 weeks (submitted for publication)

Chart showing Filaggrin expression levels and eczema risk on a blue background

Build a Stronger Skin Barrier with Skin Barrier Support L-Histidine Gummy Bears (Kids: 4-12y)

We know that classic eczema (atopic dermatitis), is a chronic skin condition where the skin barrier is weakened or disrupted. This can lead to a cycle of inflammation, redness, and itchiness. Scratching further weakens the skin barrier, which can worsen the condition and lead to infections.

The filaggrin gene (filament aggregating protein) plays an important role in maintaining skin barrier integrity, preventing de-hydration, as well as preventing pathogens and irritants from getting through the skin barrier.  Those with eczema may have fewer copies of the FLG gene, resulting in less functional filaggrin protein in the epidermis, less natural moisturization factor, and a leakier skin barrier. [image reference: DOI 10.1111/bjd.14997] This in turn increases water loss (skin de-hydration) and pH, inhibiting lipid-generating enzymes, which decreases skin cell adhesion (tight junctions/corneodesmosomes), deregulates skin turnover (desquamation), and decreases ceramides (the lipid matrix).



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    Plant-Based

The Antü Skin Barrier Support Supplement contains a remarkable combination of ingredients to strengthen the skin barrier. The L-histidine alone has been shown to help heal damaged skin, but together with other anti-inflammatory and supportive botanicals make this a truly unique product. The lotion has also been studied in those with sensitive skin, and is packed with active botanicals designed for impaired skin.

- Dr. Peter Lio, MD, Pediatric Dermatologist, Northwestern Medicine

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- Dr. Peter Lio, MD, Pediatric Dermatologist, Northwestern Medicine

The Antü Skin Barrier Support Supplement by Codex stands out with M3, a proprietary blend targeting skin resilience, and L-histidine, an amino acid that plays a critical role in repairing the barrier. Together, they help fortify the skin against environmental stressors while promoting a balanced, healthy complexion.

- Trisha Khanna, MD

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- Trisha Khanna, MD

For the Bia eczema collection, we have clinical results that conclusively prove the significant treatment synergy of topical and supplements in repairing the gut and skin barriers, as well as alleviating itch.

Professor Philippe Humber MD FAAD

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Professor Philippe Humber MD FAAD

Frequently Asked Questions

Daily dietary supplement formulated to address skin barrier deterioration from stress and the exposome (allergens, pollution, UV, secondhand smoke, detergents). It helps restore a weakened skin barrier to reduce trans-epidermal water loss, increase hydration, and improve barrier cohesion (desquamation).

They key actives are:

  • L-Histidine: skin soothing amino acid which supports the repair of damaged skin barrier. It is used by the body to make the protein filaggrin, a key building block of the skin barrier, as well as make Natural Moisturization Factor (NMF) used by the skin to help attract and retain moisture.  
  • Vitamins: contains nutritionally meaningful levels of vitamin D (as cholecalciferol), vitamin E (as d-alpha tocopheryl acetate), B2 (riboflavin), B3 (niacin) and B7 (biotin)
  • Minerals: contains nutritionally meaningful levels of zinc (as zinc citrate) to help
    relieve eczema symptoms for children suffering from a deficiency.

In self-assessments during our customer surveys:
• 100% agree skin condition improved
• 95% agree skin felt soothed, less dry, and itched less
• 90% agree sleep duration and quality improved

Customer reviews